Parents ask me this all the time: Motrin or Tylenol for fever? Here's my pediatric naturopathic perspective: Motrin treats inflammation, which often drives fever It lasts longer, so fewer doses Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Reaching for Tylenol when baby is fussy? Here's some information worth knowing. A baby's liver isn't fully mature until around 2 years old Meaning their ability to process certain substances is still Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health TYLENOL [Acetaminophen] metabolism A lot of GLUTATHIONE is needed to deal with the Oxidative Stress generated by the CYP 450 metabolism of Tylenol. When people go to the ER for Tylenol Overdose TYLENOL [Acetaminophen APAP]why it may cause harm Tylenol should likely be avoided in excess by genetically vulnerable children. GENETICALLY VULNERABLE likely meanschildren with limited supplies of GLUTATHIONE. The problem with TYLENOL