An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Pigmented Lesions of the Oral Mucosa Pocket Dentistry This is a picosecond laser treatment of labial melanotic macules on the gingiva. Note the green flashes of the 532 nm laser as well as the immediate tissue whitening of the treated area. This COM August 2004 Diagnosis UW School of Dentistry Macular Pigmented Oral Mucosal Lesions: An Amalgam Tattoo Case Report Dentistry Today